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Addressing Unmet Needs in Woundcare Management

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Thursday, November 3, 2022, 10 am

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Electrical and Computer Engineering Seminar

Dr. Shekhar Bhansali

Distinguished University Professor and Lucent CALA Technologies Distinguished Professor
Department of Electrical and Computer Engineering
Florida International University


Wounds that do not heal over long periods of time (3 months) are classified as Chronic wounds. They manifest themselves in patients that have underlying diseases like poorly controlled diabetes. Chronic wounds need to be managed to prevent complications, preserve tissue function, and facilitate healing. Current practice for wound evaluation and wound management includes visually recording the wound area and wound depth to assess healing progress. The need to visit a clinic at least once every week results in poor patient compliance and long term complications with inferior health outcomes.

Our research focuses on leveraging advances in electrochemical sensing, fabrication techniques and electronics to develop a new class of affordable wound dressings that enable quantitative measurements of markers of wound healing. In this talk, a novel sensor chemistry, its in-vitro and initial in-vivo results are presented. This biosensor was fabricated by immobilizing uricase (UOx), a natural catalyst for Uric Acid (an indicator for wound status) as the enzyme. UA is immobilized on a flexible electrode along with Au nanoparticles and multi-walled carbon nanotubes (MWNT) and gold nanoparticles (Au) in an FCA matrix to ensure seamless electron transfer. The sensor was attached to gauze and used on patients for proof of principle.


Bhansali is a former NSF Electrical Communications and Cyber Security (ECCS) Division director (2020-22). He has advised 25 postdoctoral fellows and 65 PhD and master's students. He is an elected fellow of AAAS, AIMBE, ECS, NAI and IOP. His visit is sponsored by the ECE department at Michigan Tech.

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