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VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Illuminating the Mechanical Adaptation of Musculoskeletal Inte
 rfaces
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260520T003806Z
UID:tag:localist.com\,2008:EventInstance_44374342104533
DTSTART:20230929T200000Z
DTEND:20230929T210000Z
DESCRIPTION:Biomedical Engineering Research Seminar\n\nDr. Megan Killian\n\
 nUniversity of Michigan\n\nAbstract\n\nThe bones of our skeleton get their
  shape from the transfer of mechanical loads applied by muscles at tendon 
 attachment sites. These tendon-bone attachments are subject to dynamic loa
 ds throughout our lifespan\, and changes to bone shape are often most sens
 itive during periods of growth and development. The research she will pres
 ent focuses on the important role of mechanical loading during growth of t
 he tendon and its attachment to bone. She will highlight some of her recen
 t work using optogenetic tools\, which can be leveraged to induce skeletal
  muscle contractions simply with blue light. This allows us to study how c
 hanges in the structure and function of tendon and bone are influenced by 
 increased mechanical loading in live animals.\n\nBio\n\nShe is an alumna o
 f Michigan Tech—BS ‘05 and PhD ’10 in Biomedical Engineering—and a
  former member of the Women’s Cross Country\, Nordic Ski\, and Track and
  Field teams. In her current role as an Assistant Professor in Orthopaedic
  Surgery at the University of Michigan\, she lead an independent research 
 laboratory focused on pediatric musculoskeletal biology and biomechanics. 
 Prior to starting her laboratory at Michigan\, she was a postdoctoral fell
 ow at Washington University in St. Louis from 2011–2015\, and first esta
 blished her research program in 2016 at the University of Delaware in the 
 Department of Biomedical Engineering. She relocated her laboratory to Mich
 igan in February 2020. She is the 2024 chair of the Student Paper Competit
 ion for the Summer Biomechanics\, Bioengineering\, and Biotransport Confer
 ence\, and she has been an active member of SB3C/ASME Bioengineering Divis
 ion since 2008. As a PI\, she has received several competitive\, independe
 nt fundings from the National Institutes of Health and the National Scienc
 e Foundation\, including the NSF CAREER Award. Her laboratory focuses on t
 he remodeling and damage of tendon and its attachment to bone (i.e.\, enth
 esis) in response to muscle loading during growth and aging in mice. Stude
 nts in her laboratory have completed training in biomedical engineering\, 
 mechanical engineering\, animal biosciences\, integrative physiology and b
 ioinformatics and have continued careers or training in STEM fields\, and 
 include clinicians\, veterinarians\, and research scientists and engineers
  at institutions like Booz Allen Hamilton\, University of Pennsylvania\, C
 ornell University\, Rush University\, the Children's Hospital of Philadelp
 hia\, Merck\, Globus\, and Qiagen.
GEO:47.119053;-88.545006
LOCATION:Minerals and Materials Engineering Building (M&M)\, 610
SUMMARY:Illuminating the Mechanical Adaptation of Musculoskeletal Interface
 s
URL;VALUE=URI:https://events.mtu.edu/event/illuminating_the_mechanical_adap
 tation_of_musculoskeletal_interfaces
CATEGORIES:Academics
CATEGORIES:Lectures/Seminars
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