BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Nanotechnology-Enabled Biology
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260721T071031Z
UID:tag:localist.com\,2008:EventInstance_4081513
DTSTART:20181113T160000Z
DTEND:20181113T170000Z
DESCRIPTION:Using Materials to Orchestrate Wound Repair\n\nMaterials Scienc
 e and Engineering Seminar\n\nDr. Ben Almquist\nDepartment of Bioengineerin
 g\nImperial College London\, UK\n\nAbstract: Recent advances in nanoscienc
 e have enabled us to create materials and devices that interact with biolo
 gical systems across every relevant length scale\, whether at the level of
  individual proteins or hierarchical tissues. However\, biological systems
  such as tissues integrate transient biological signalling to drive growth
  and repair. Therefore\, to create seamless biotic- abiotic interfaces bet
 ween tissues and engineered materials\, there is a need for new methods th
 at enable us to direct biological influence over time. In this talk\, I wi
 ll explore how we can begin the blur the interfaces between synthetic devi
 ces and biological systems by rationally engineering the interaction\, bot
 h spatially and temporally. By combining aspects of materials science\, na
 notechnology\, and self-assembly\, we are now able to design ‘smart’ m
 aterials that control and coordinate the temporal delivery of biomolecules
 \, both from 2D surfaces and within 3D matrices\, enabling new possibiliti
 es for both in vitro cell cultures and in vivo environments. Specifically\
 , I will cover our approaches for controlling the delivery of growth facto
 rs in 3D using DNA nanotechnology\, temporally coordinating the transient 
 knockdown of multiple genes via self-assembled biomaterials\, and efforts 
 using nanodevices to elucidate fundamental biological principals regarding
  the role of microRNAs\, small non-coding RNAs implicated in a range of di
 seases\, in promoting pathological cell signalling.\n\nBio: Dr Almquist re
 ceived his BS in Materials Science & Engineering from Michigan Tech in 200
 4\, followed by an MS and PhD in Materials Science & Engineering from Stan
 ford University in 2007 and 2011\, respectively. During his time at Stanfo
 rd\, Dr Almquist pioneered the development of bioinspired nanoprobes that 
 enable the fusion of silicon-based devices into cellular membranes. This r
 esearch led to his appointment as a Research Fellow in the joint NSF-Stanf
 ord-IBM Center for Probing the Nanoscale\, along with being awarded the Ma
 terials Research Society Graduate Student Gold Award. Following his time a
 t Stanford\, Dr Almquist moved to the Koch Institute for Integrative Cance
 r Research and Institute for Soldier Nanotechnologies at MIT\, where as an
  NIH Ruth L. Kirschstein Postdoctoral Fellow he developed self-assembled b
 iomaterials for combinatorial biologic delivery to chronic wounds. In 2014
 \, he moved to Imperial College London as a Lecturer (Assistant Professor)
  in the Department of Bioengineering\, where his group is pushing the deve
 lopment of nanomaterial-based approaches for addressing longstanding quest
 ions across the biosciences. This work has led to Dr Almquist being recogn
 ised as a 2017 Emerging Investigator in the journal Biomaterials Science\,
  along with receiving the 2016 Outstanding Young Alumni Award from Michiga
 n Tech. In addition to his research\, Dr Almquist has a passion for teachi
 ng and has been recognised as a Fellow of the Higher Education Academy in 
 the UK.
GEO:47.119053;-88.545006
LOCATION:Minerals and Materials Engineering Building (M&M)\, 610
SUMMARY:Nanotechnology-Enabled Biology
URL;VALUE=URI:https://events.mtu.edu/event/nanotechnology-enabled_biology
CATEGORIES:Academics
CATEGORIES:Lectures/Seminars
END:VEVENT
END:VCALENDAR