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Novel Bioresorbable Metallic Biomaterials for Regeneration

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Friday, October 25, 2019, 3 pm

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Biomedical Engineering Graduate Seminar

The Department of Biomedical Engineering presents

Donghui (Don) Zhu, PhD

SUNY Empire Innovation Associate Professor
Department of Biomedical Engineering & Institute for Engineering-Driven Medicine
Stony Brook University—SUNY New York

Abstract: Innovations in metallic biomaterials have attracted remarkable attention for their potentials as orthopedic implants, cardiovascular interventional devices, and tissue engineering scaffolds, due to their high strength and toughness compared with polymers and ceramics. Traditional metallic biomaterials with high corrosion resistance, such as titanium alloys, stainless steels, and cobalt-chromium are generally permanent implants, and may cause chronic deleterious effects. Thus, a second operation may be necessary to extract the implant, resulting in additional injury and expense. Biodegradable metals (Mg, Zn, Fe) are an alternative approach to the traditional paradigm of corrosion resistant metals. They can corrode gradually while maintaining mechanical integrity during the critical tissue healing phase, and fully dissolve upon fulfilling their mission. Lately, our research focuses on the emerging Zn-based biomaterials as innovative bioresorbable medical implants and devices, typically for stent, wound closure, and orthopedic applications.

Bio: Dr. Donghui (Don) Zhu earned his Bachelor degree at East China University of Technology and Science, and Doctorate in Bioengineering at University of Missouri-Columbia. Following his Ph.D., Dr. Zhu was trained at University of Rochester medical center on regenerative medicine for vascular applications. Dr. Zhu has a broad research interest in biomaterials, cardiovascular diseas-es, musculoskeletal disorders, as well as neuroscience and engineering. He has secured over $6 million total federal research funding in the past five years, co-authored more than 70 peer-reviewed journal articles and book chapters. Dr. Zhu is an editor or on editorial boards of several scientific journals. He also serves in numerous grant proposal review panels including NIH, NSF, FDA, and NASA.

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